Phenylpyruvic Oligophrenia. Report of a Case in an Infant with Quantitative Chemical Studies of the Urine.
نویسندگان
چکیده
منابع مشابه
An improved test for phenylketonuria.
HENYLKETONURIA (phenylpyruvic oligophrenia) is a metabolic disorder first recognized by Foiling (1) approximately 25 years ago. He found that two mentally retarded children in. the same family excreted urine containing a substance which gave a green color with ferric chloride. This substance was identified as phenylpyruvic acid. It has subsequently been recognized that in phenylketonuria a bloc...
متن کاملStudies on phenylpyruvic oligophrenia; the position of the metabolic error.
Phenylpyruvic oligophrenia is a disease characterized clinically by mental defect and biochemically by the presence in the urine of phenylpyruvic acid (l-3) and phenylalanine (4, 5). In addition, abnormally high amounts of phenylalanine are found in the blood (4, 6). Although there is little doubt that the condition is an error of metabolism of phenylnlanine, which is inborn and inherited as a ...
متن کاملStudies on Phenylpyruvic Oligophr.eni.~* the Position of the Metabolic Error
Phenylpyruvic oligophrenia is a disease characterized clinically by mental defect and biochemically by the presence in the urine of phenylpyruvic acid (l-3) and phenylalanine (4, 5). In addition, abnormally high amounts of phenylalanine are found in the blood (4, 6). Although there is little doubt that the condition is an error of metabolism of phenylnlanine, which is inborn and inherited as a ...
متن کاملStudies On
Phenylpyruvic oligophrenia is a disease characterized clinically by mental defect and biochemically by the presence in the urine of phenylpyruvic acid (l-3) and phenylalanine (4, 5). In addition, abnormally high amounts of phenylalanine are found in the blood (4, 6). Although there is little doubt that the condition is an error of metabolism of phenylnlanine, which is inborn and inherited as a ...
متن کاملThe hydroxylation of phenylalanine and antipyrine in phenylpyruvic oligophrenia.
In normal individuals the major portion of ingested phenylalanine is converted into tyrosine. In the disease phenylpyruvic oligophrenia, however, ingested phenylalanine is converted mainly into phenylpyruvic and phenyllactic acids (l), which are excreted in the urine. This phenomenon has been ascribed to the inability of the body to convert phenylalanine to tyrosine (2) and a consequent shuntin...
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ورودعنوان ژورنال:
- The Journal of clinical investigation
دوره 22 1 شماره
صفحات -
تاریخ انتشار 1943